I disagree that life is self-sustaining. One must make choices in order to live, an evasion of the necessity to make choices cannot lead one to sustain his life.
If the purpose of one's life is to achieve immortality and to prolong life and that that was the value above all other values, then there definitely is circular issues. Transhumanism, at least the position taken by some in this thread, holds that all values are impossible without life and that, therefore, man must look to prolong his life above all else. This means that the value of "prolonging life" implicitly rises above the Objectivist values that life is an end in itself. This can lead to rights violation and neglecting to enjoy one's life for what it is.
Correct me if I am wrong, please, I am trying to learn