The mind-independent universe is mass-energy, not philosopher-armchair substance. Knowledge of mass-energy and evidence for its amount in the whole universe being conserved back to and including the Initial Singularity is a glorious fruitful quest of science alone.
Whether there are extensionless points in spacetime is, in the armchairs of philosophers, as stuck in the mud as all the centuries they wasted over the question of whether matter was atomic or continuous. Science got the answers and subtleties of that and delivered a solid stage for bringing the world into our service.
Elementary particle physics has it that leptons, in their particle mode, are extensionless particles, perfect points of mass. The old sayings of philosophers that extension is more fundamental than weight is sensibly (on account of modern science) left back in those moldy old armchairs.
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Nietzsche had read, in 1876 and 1883, a renovation of Schopenhauer’s system that made it less metaphysical. That was Philipp Mainländer’s Philosophy of Redemption (1876),5 in which the author claimed that throughout nature “instead of one metaphysical will, there are many individual (and immanent) wills that continually struggle with one another” (Brobjer 2008, 69). That is an opening for an individualistic theoretical employment of will in nature, in nature more widely than in intellectual animals such as man.
5. In this title, I have translated Erlösung as Redemption because that is how the term is rendered by translators of Schopenhauer. However, it would also be reasonable to translate Erlösung as Deliverance. Schopenhauer and Mainländer were atheists and thought that death is the end of the individual. They thought of death as deliverance from the suffering pervasive in life.
Brobjer, T. 2008. Nietzsche’s Philosophical Context. U of Ill Press.